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Fig. 5 | Virology Journal

Fig. 5

From: Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B

Fig. 5

The associations between mRNA level and methylation level of GPX4 in PBMCs and mRNA level of STING in PBMCs, and IFN-β expressive in serum. Significant correlation was observed between the mRNA level of GPX4 and mRNA level of STING in PBMCs (a Spearman’s r = 0.4203, P<0.0001), and IFN-β expressive in serum (b Spearman’s r = 0.3469, P<0.0001). And significant correlation was observed between the PMR value of GPX4 promoter and mRNA level of STING in PBMCs (c Spearman’s r = − 0.4508, P<0.0001), and IFN-β serum expression level (d Spearman’s r = − 0.2255, P = 0.0081),ns, P>0.05; *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001

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Virology Journal

ISSN: 1743-422X