Table 1 Characteristics of fully vaccinated, partially vaccinated, and unvaccinated hospitalized COVID-19 patients

Mean age (years)

54.8 ± 18.6

58.7 ± 15.9

65.4 ± 15.9

A vs. C* <0.001

Sex

0.11

Male

Female

41.1% (92)

58.9% (132)

51.7% (15)

48.3% (14)

53.4% (47)

46.6% (41)

Race

0.002

White

Black/African American

Other

39.7% (89)

52.2% (117)

8% (18)

37.9% (11)

58.6% (17)

3.4% (1)

62.5% (55)

36.4% (32)

1.1% (1)

Insurance Type

0.041

Commercial

Medicare

Medicaid

129 (57.6%)

81 (36.2%)

14 (6.3%)

15 (51.7%)

12 (41.4%)

2 (6.9%)

35 (39.8%)

49 (55.7%)

4 (4.5%)

Mean body mass index

31.1 ± 9.3

38.9 ± 17.1

30.8 ± 7.8

B vs. A;

B vs. C.

< 0.001

Obesity (n = 181)

114 (50.9%)

18 (62.1%)

49 (55.7%)

0.4

Median CWIC

0.0 (0.0, 1.75)

1.0 (0.0, 1.0)

1.0 (0.0, 3.0)

< 0.001

Prior MI (n = 43)

25 (11.2%)

2 (6.9%)

16 (18.2%)

0.2

CHF (n = 34)

16 (7.1)

2 (6.9%)

16 (18.2%)

0.01

PVD (n = 56)

32 (14.3)

5 (17.2%)

19 (21.6%)

0.3

CVD (n = 76)

44 (19.6)

6 (20.7)

26 (29.5)

0.2

Diabetes without complications (n = 76)

46 (20.5%)

10 (34.5%)

20 (22.7%)

0.2

Diabetes with complications (n = 30)

17 (7.6%)

2 (6.9%)

11 (12.5%)

0.4

Asthma (n = 28)

18 (8%)

4 (13.8%)

6 (6.8%)

0.4

COPD (n = 47)

31 (13.8%)

5 (17.2%)

11 (12.5%)

0.8

Renal disease (n = 40)

19 (8.5%)

1 (3.4%)

20 (22.7%)

< 0.001

Dementia (n = 21)

12 (5.4%)

1 (3.4%)

8 (9.1%)

0.4

Any malignancy (n = 29)

14 (6.3%)

2 (6.9%)

13 (14.8%)

0.05

HIV (n = 6)

3 (1.3%)

1 (3.4%)

2 (2.3%)

0.7

Hypertension (n = 203)

124 (55.4%)

15 (51.7%)

64 (72.7%)

0.013

Steroid Use at home (n = 10)

70% (7)

0% (0)

30% (3)

-

Current Smoker (n = 55)

28 (12.5%)

11 (37.9%)

16 (18.2%)

0.002

Drug Use (n = 13)

9 (4%)

1 (3.4%)

3 (3.4%)

0.9

Vital signs on admission

Mean Temperature

37.2 ± 1.0

37.2 ± 0.9

37 ± 0.7

0.3

Mean Heart rate

101.1 ± 23.8

100.4 ± 21.9

91.2 ± 19.1

A vs. C

0.002

Mean Respiratory rate

20.3 ± 5.7

20.5 ± 5.3

19.6 ± 4.8

0.6

Mean Oxygen saturation

94.3 ± 5.9

95 ± 4.5

95.7 ± 5.3

0.1

Laboratory findings on admission

Mean White blood cell count

7.7 ± 4.6

7.7 ± 5.1

8.7 ± 6.3

0.3

Mean Hemoglobin

12.8 ± 2.3

12.8 ± 2.9

12.1 ± 2.1

A vs. C 0.05

Mean Platelet count

228.7 ± 93.4

217.5 ± 81.8

219.9 ± 84.1

0.7

Mean Total protein

7.1 ± 1.1

6.7 ± 1

6.7 ± 0.9

A vs. C 0.01

Mean Albumin

3.6 ± 0.6

3.7 ± 0.6

3.6 ± 0.6

0.9

Mean C-reactive protein

90.1 ± 81

77.2 ± 68.6

65.4 ± 75.8

0.09

Chest imaging on admission No. (%)

Abnormal chest x-ray (n = 198)

143 (71.1%)

16 (64%)

39 (48.8%)

0.002

Abnormal CT scan (n = 118)

89 (92.7%)

7 (77.8%)

22 (71%)

0.006