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Table 3 Sensitivity analyses of adverse events based on study types

From: Effectiveness of azvudine in reducing mortality of COVID-19 patients: a systematic review and meta-analysis

AE

RCTs

Cohort studies

No. of Studies

OR (95%CI)

I2

P

No. of Studies

OR (95%CI)

I2

P

Total AEs

3

0.80 (0.55–1.17)

9.5%

0.25

3

2.45 (0.73–8.21)

77%

0.15

Digestive system

3

1.08 (0.49–2.35)

15%

0.85

3

4.84 (0.85–27.7)

78%

0.08

Chest discomfort

3

0.51 (0.18–1.45)

0

0.86

1

NA

  

Neurological system

2

NA

  

2

NA

  

Elevated liver enzymes

2

NA

  

2

NA

  

Elevated creatinine

1

NA

  

2

NA

  
  1. AE = adverse event; RCT = randomized controlled study; NA = no pooled analysis could be conducted because of the number of studies being less than 3
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Virology Journal

ISSN: 1743-422X