Table 1 CKD and its association with sever COVID-19 in the MR analyses
From: Severe COVID-19 and chronic kidney disease: bidirectional mendelian randomization study
Exposure | Outcome | No. of SNPs | Methods | OR (95% CI) | β (SE) | p |
|---|---|---|---|---|---|---|
Forward MR analyses | ||||||
CKD | sever COVID-19 | 4 | IVW | 1.28(1.04,1.58) | 0.25(0.11) | 0.018 |
MR-Egger | 1.12(0.48,2.59) | 0.11(0.43) | 0.822 | |||
Weighted median | 1.30(1.01,1.67) | 0.26(0.13) | 0.038 | |||
Weighted mode | 1.28(0.88,1.88) | 0.25(0.19) | 0.286 | |||
Reverse MR analyses | ||||||
sever COVID-19 | CKD | 6 | IVW | 1.03(0.96,1.10) | 0.03(0.03) | 0.395 |
MR-Egger | 1.03(0.89,1.23) | 0.03(0.09) | 0.737 | |||
Weighted median | 1.05(0.98,1.13) | 0.05(0.04) | 0.2 | |||
Weighted mode | 1.05(0.97,1.14) | 0.05(0.04) | 0.25 | |||