Systemic perturbations in amino acids/amino acid derivatives and tryptophan pathway metabolites associated with murine influenza A virus infection

Table 3 Changes in levels of 8 neurotransmitters between control and infected mice at the acute (7 dpi), resolution (14 dpi), and recovery stages (21 dpi) of IAV infection

Amino acids/ neurotransmitters	Excitatory or inhibitory	Changes during infection
Aspartic acid	Excitatory	No significant difference
β-alanine	Inhibitory	No significant difference
Cysteine	Excitatory	Decrease at 7 dpi
GABA	Inhibitory (adult); excitatory (developing)	No significant difference
Glycine	Inhibitory	Decrease at 7 dpi Increase at 21 dpi
Glutamic acid	Excitatory	No significant difference
Taurine	Inhibitory	Increase at 7 dpi
Glycine	Inhibitory	Decrease at 7 dpi Increase at 21 dpi
Dopamine	Both excitatory and inhibitory	Decrease at 14 dpi
Serotonin	Inhibitory	No significant difference

ISSN: 1743-422X