Table 1 EC50 values for SKAI-DS84 and bamlanivimab based on SARS-CoV-2 WT and variant luciferase-based pseudovirus assays
Variants | ||
|---|---|---|
Antibody | SKAI-DS84 | Bamlanivimab |
EC50 (μg/mL) | EC50 (μg/mL) | |
WT | 0.002 | 0.005 |
P1 (Gamma) | 0.004 | > 10 |
B.1.617.2 (Delta) | 0.0465 | > 10 |
C.37 (Lambda) | 0.0026 | > 10 |
B.621 (Mu) | 0.0025 | > 10 |
B.1.1.529 (BA1) | 0.1643 | > 10 |
B.1.1.529 (BA2) | 0.0124 | > 10 |
B.1.1.529 (BA4/5) | 0.3217 | > 10 |