Fig. 5From: Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variantsSKAI-DS84 may bind to the quaternary structure of the SARS-CoV-2 RBD. Surface plasmon resonance analysis of SKAI-DS84 against SARS-CoV-2 RBD and its variants. The RBDs of SARS-CoV-2 (a) WT, b B.1.617.2, c B.1.1.529 (BA.1), d BA.2, and e BA4/5 were immobilized on the biosensor. Subsequently, two-fold serially diluted SKAI-DS84 was allowed to flow over the biosensor surface. RBD, receptor-binding domain; WT, wild-type; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2Back to article page