Fig. 3
From: Aspirin inhibits rotavirus replication and alters rat gut microbial composition
Determination of the antiviral activity of long-term aspirin administration in the rotavirus-infected rat model
Forty rats were randomly distributed into the control (NC) (oral 0.5% carboxylmethylcellulose solution 1 ml) and ASP group (oral aspirin). After 6 months, the two groups were infected with the same amount of SA11 (106 PFU/ml per day) for 30 days (NC-RV and ASP-RV). The viral titer and virus RNA in rat fecal were evaluated on 6, 12, 18, 24, 30 days by fluorescent assay (A) and qRT-PCR (B). RV, rotavirus; ASP, aspirin