Skip to main content

Table 4 Risk factors related to longer length of hospital stay. Univariate and multivariate Cox regression analysis

From: Outcomes of viral coinfections in infants hospitalized for acute bronchiolitis

 

Univariable analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Sex (male)

0.956

0.870–1.051

0.354

   

Gestational age (weeks)

1.073

1.029–1.120

< 0.001

1.077

1.033–1.122

< 0.001

Birth weight (g)

1.000

1.000–1.000

0.033

1.000

1.000–1.000

0.766

Weight at admission (Kg)

1.147

1.093–1.203

< 0.001

1.003

0.904–1.112

0.960

Age (months)

1.057

1.032–1.083

< 0.001

1.062

1.035–1.091

< 0.001

Underlying disease

0.685

0.484–0.971

0.033

0.578

0.400–0.836

0.004

Prematurity

0.750

0.577–0,974

0.031

1.049

0.705–1.562

0.812

Caesarean section

0.951

0.779–1.161

0.620

   

Personal history atopy

0.916

0.637–1.319

0.638

   

Apnea

0.417

0.275–0.632

< 0.001

0.725

0.465–1.130

0.155

Sepsis

0.275

0.129–0.585

< 0.001

0.253

0.117–0.548

< 0.001

Breastfeeding

0.910

0.748–1.106

0.341

   

*Ventilatory support

0.347

0.283–0.425

< 0.001

0.332

0.267–0.413

< 0.001

PICU admission

0.413

0.329–0.518

< 0.001

0.863

0.623–1.196

0.376

RSV

0.883

0.707–1.104

0.275

0.979

0.747–1.283

0.877

Rhinovirus/enterovirus

1.038

0.853–1.262

0.713

   

Coronavirus

0.679

0.486–0.949

0.023

0.770

0.523–1.134

0.185

Bocavirus

0.802

0.574–1.120

0.195

0.956

0.627–1.457

0.833

Parainfluenza

0.812

0.568–1.161

0.254

   

Human Metapneumovirus

0.766

0.511–1.148

0.197

0.740

0.486–1.126

0.159

Adenovirus

1.293

0.815–2.049

0.275

   

Infuenza

0.774

0.481–1.243

0.289

   

Viral coinfection

0.769

0.635–0.932

0.007

   

†Viral co-detections

      

None

  

0.011

  

0.002

2 Virures

≥ 3 Viruses

0.831

0.644

0.672–1.029

0.474–0.875

0.090

0.005

0.858

0.568

0.688–1.071

0.410–0.785

0.176

< 0.001

  1. h and 95% CIs are from Cox regression. Bold indicates statistical significance (p < 0.05)
  2. RSV Respiratory syncytial virus
  3. * Ventilatory support includes: HFNC oxygen therapy, NIV and IMV.
  4. † Viral co-detection: Reference group = none
Back to article page

Virology Journal

ISSN: 1743-422X