Table 3 Clinical characteristics and treatments of patients with bronchiolitis associated to viral single infection compared with viral coinfection
From: Outcomes of viral coinfections in infants hospitalized for acute bronchiolitis
Single virus n = 270 | Coinfections n = 175 | p-value | |
|---|---|---|---|
Sex (%) | 0.003 | ||
Female Male | 97 (35.9) 173 (64.1) | 88 (50.3) 87 (49.7) | |
Gestational age (weeks) | 39 [37–40] | 39 [37–40] | 0.721 |
Birth weight (grams) | 3.1 [2.75–3.47] | 3.13 [2.72–3.44] | 0.566 |
Age (months) | 2.32 [1.34–4.35] | 2.79 [1.45–5.45] | 0.074 |
Weight at admission (Kilograms) | 5.16 [4.15–6.23] | 5.34 [4.28–6.80] | 0.167 |
Prematurity (%) | 42 (15.6) | 25 (14.3) | 0.765 |
Type of delivery (% caesarean section) | 82 (30.4) | 61 (34.9) | 0.348 |
Underlying disease (%) | 22 (8.1) | 13 (7.4) | 0.783 |
Personal history atopy (%) | 19 (7) | 14 (8) | 0.687 |
Family history of atopy (%) | 48 (17.8) | 36 (20.6) | 0.489 |
Siblings (%) | 169 (62.6) | 120 (68.6) | 0.139 |
Breastfeeding | 106 (39.3) | 58 (33.1) | 0.152 |
Fever ≥ 38ºC (%) | 115 (42.6) | 107 (61.1) | < 0.001 |
Food refusal (%) | 148 (54.8) | 109 (62.3) | 0.242 |
Apnea (%) | 16 (5.9) | 9 (5.1) | 0.726 |
C reactive Protein (mg/L) n = 424 | 6.9 [1.4–19.6] | 14.6 [4.53–36.1] | < 0.001 |
Urinary tract infection (%) | 9 (3.3) | 11 (6.3) | 0.142 |
Sepsis (%) | 2 (0.7) | 6 (3.4) | 0.037 |
Antibiotic treatment (%) | 90 (33.3) | 67 (38.3) | 0.286 |
Consolidation on chest X-Ray n = 260 (%) | 33/163 (20.2) | 30/97 (30.9) | 0.052 |
Respiratory support (%) | |||
None Only LFNC oxygen therapy Only HFNC oxygen therapy NIV IMV | 28 (10.4) 140 (51.9) 55 (20.4) 44 (16.3) 3 (1.1) | 17 (9.7) 85 (48.6) 36 (20.6) 36 (20.6) 1 (0.6) | 0.823 0.499 0.959 0.251 1 |
PICU admission (%) | 61 (22.6) | 44 (25.1) | 0.536 |
PICU Length of stay (days) | 0.078 | ||
Length of hospital stay (days) | 0.004 |