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Table 1 Characteristics of study participants between three groups with different HIV-1 genotypes

From: HIV-1 drug resistance and genetic transmission network among newly diagnosed people living with HIV/AIDS in Ningbo, China between 2018 and 2021

Characteristics

All participants

n (%)

HIV-1 genotypes

χ2

P value

CRF01_AE

n (%)

CRF07_BC

n (%)

CRF08_BC

n (%)

C

n (%)

CRF55_01B

n (%)

Others*

n (%)

Overall

1006(100)

339(100)

409(100)

69(100)

54(100)

50(100)

85(100)

  

Gender

         

Male

868(86.3)

298(87.9)

366(89.5)

50(72.5)

42(77.8)

47(94.0)

65(76.5)

25.799

< 0.001

Female

138(13.7)

41(12.1)

43(10.5)

19(27.5)

12(22.2)

3(6.0)

20(23.5)

  

Age (years)

         

< 25

139(13.8)

50(14.7)

63(15.4)

5(7.2)

3(5.6)

7(14.0)

11(12.9)

51.906

< 0.001

25~

356(35.4)

130(38.3)

149(36.4)

14(20.3)

20(37.0)

25(50.0)

18(21.2)

  

40~

354(35.2)

110(32.4)

139(34.0)

26(37.7)

24(44.4)

18(36.0)

37(43.5)

  

≥ 60

157(15.6)

49(14.5)

58(14.2)

24(34.8)

7(13.0)

0(0)

19(22.4)

  

Marital status

         

Single

377(37.5)

135(39.8)

166(40.6)

16(23.2)

16(29.6)

20(40.0)

24(28.2)

17.299

0.068

Married

431(42.8)

139(41.0)

160(39.1)

35(50.7)

28(51.9)

24(48.0)

45(52.9)

  

Divorce or death

198(19.7)

65(19.2)

83(20.3)

18(26.1)

10(18.5)

6(12.0)

16(18.8)

  

Education level

         

Middle school or less

622(61.8)

208(61.4)

242(59.2)

57(82.6)

35(64.8)

22(44.0)

58(68.2)

22.299

< 0.001

High school or above

384(38.2)

131(38.6)

167(40.8)

12(17.4)

19(35.2)

28(56.0)

27(31.8)

  

Nationality

         

Han

964(95.8)

329(97.1)

392(95.8)

64(92.8)

51(94.4)

47(94.0)

81(95.3)

4.534

0.450

Others

42(4.2)

10(2.9)

17(4.2)

5(7.2)

3(5.6)

3(6.0)

4(4.7)

  

Location

         

Local

438(43.5)

153(45.1)

167(40.8)

36(52.2)

27(50.0)

19(38.0)

36(42.4)

5.253

0.386

Non local

568(56.5)

186(54.9)

242(59.2)

33(47.8)

27(50.0)

31(62.0)

49(57.6)

  

Route of infection

         

Heterosexual transmission

532(52.7)

185(54.6)

193(47.2)

56(81.2)

33(61.1)

17(34.0)

48(56.5)

42.681

< 0.001

Homosexual transmission

470(46.7)

152(44.8)

215(52.6)

13(18.8)

20(37.0)

33(66.0)

37(43.5)

  

Others

4(0.6)

2(0.6)

1(0.2)

0(0)

1(1.9)

0(0)

0(0)

  

Number of sexual partners in a life time

  

<6

800(79.5)

270(79.6)

327(80.0)

52(75.4)

44(81.5)

37(74.0)

70(82.4)

4.921

0.896

6 ~ 10

130(12.9)

45(13.3)

50(12.2)

9(13.0)

6(11.1)

10(20.0)

10(11.8)

  

≥11

76(7.6)

24(7.1)

32(7.8)

8(11.6)

4(7.4)

3(6.0)

5(5.9)

  

CD4,cell/ul

         

< 200

379(37.7)

147(43.4)

138(33.7)

25(36.2)

19(35.2)

14(28.0)

36(42.4)

19.400

0.035

200~

525(52.2)

161(47.5)

236(57.7)

32(46.4)

30(55.6)

29(58.0)

37(43.5)

  

≥ 500

102(10.1)

31(9.1)

35(8.6)

12(17.4)

5(9.3)

7(14.0)

12(14.1)

  

Transmitted drug resistance

         

Sensitive

945(93.9)

313(92.3)

399(97.6)

57(82.6)

49(90.7)

47(94.0)

80(94.1)

25.686

< 0.001

Resistance

61(6.1)

26(7.7)

10(2.4)

12(17.4)

5(9.3)

3(6.0)

5(5.9)

  
  1. *: B,URFs, CRF85_BC,CRF01_BC,CRF59_01B, CRF67_01B and CRF68_01B