Fig. 7From: Unveiling the biology of defective viral genomes in vitro and in vivo: implications for gene expression and pathogenesis of coronavirusSequences flanking the recombination points of DVGs are AU-rich. (A)-(C) Left panel: Characterization of the sequence flanking the recombination points (RP1 and RP2) of in BCoV-and MHV-A59-infected cells and MHV-A59 infected mice based on databases obtained from nanopore direct RNA sequencing. Right panel: Correspondence between the AU-rich sequence and the occurrence of recombination point. X-axis represents the percentage of AU sequence flanking the recombination points and y-axis represents the percentage of RP occurrence. RP, recombination point. The results are derived from the two biological replicatesBack to article page