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Fig. 5 | Virology Journal

Fig. 5

From: Unveiling the biology of defective viral genomes in vitro and in vivo: implications for gene expression and pathogenesis of coronavirus

Fig. 5

The structures of experimentally identified DVGs and the predicted encoded proteins. The numbers shown in each DVG structure are the nucleotide positions at which the recombination occurs. The dashed line indicates the truncated genome in DVG. The encoded fusion protein from D-448, D-491, D-551, D-697, D-717, D-718, D-725, D-817, D-857 and D-859 contains part of nsp1 and protein resulted from frameshift in N protein gene. The encoded fusion protein from D-492, D-678, D-722, D-816, D-823, D-839, D-842, D858 and D930 contains part of nsp1 and N protein. The encoded fusion protein from D-699 contains part of nsp1 and protein resulted from frameshift in gene from 3’UTR. The encoded fusion protein from D-861 contains part of nsp1 and protein resulted from frameshift in N protein gene and gene from 3’UTR. The encoded fusion protein from D-1013, D-1056 and D-1058 contains nsp1, part of nsp2 and protein resulted from frameshift in N protein gene. The encoded fusion protein from D-1066 contains nsp1 and part of nsp2 and N protein. The encoded fusion protein from D-498 contains part of nsp1 and complete N protein

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