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Fig. 1 | Virology Journal

Fig. 1

From: MicroRNA-194-3p impacts autophagy and represses rotavirus replication via targeting silent information regulator 1

Fig. 1

RV infection down-regulates the expression of miR-194-3p. (A) Caco-2 cells were infected with RV-Wa (MOI = 1) or DMEM (Mock), the expression of miR-194-3p was analyzed by using qRT-PCR at 0, 12, 24, 36 and 48 hpi. (B) Caco-2 cells were infected with other genotypes of RV, such as G1 (Wa), G2 (S2), G4 (Gottfried), G9 (ZTR-18), the expressions of miR-194-3p was analyzed by using qRT-PCR at 36 hpi. (C) Caco-2 cells were infected with different MOI (0.1, 0.5, 1, 2) of RV-Wa, the expressions of miR-194-3p was analyzed by using qRT-PCR at 36 hpi. (D) The expressions of miR-194-3p was measured by qRT-PCR in UV-inactivated RV-Wa infected Caco-2 cells at 36 hpi. The fold change in the transcript was calculated by normalizing the relative gene expression to U6. The data are presented as the mean ± SD. * P < 0.05; ** P < 0.01

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Virology Journal

ISSN: 1743-422X