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Fig. 2 | Virology Journal

Fig. 2

From: Dengue virus 3 genotype I (GI) lineage 1 (L1) isolates elicit differential cytopathic effect with syncytium formation in human glioblastoma cells (U251)

Fig. 2

Amino Acid Divergences and Structural Analysis of DENV3 MG-20 and DENV3 PV_BR. 2A. Mutations Table. 2B, and C. DENV3 G1 structure modeled using the 4GSX template from Protein Data Bank. The structure is presented in a surface representation, enabling observation of mutations on the outer face of the protein (2B). In 3C, the structure is presented in a cartoon representation, allowing observation of mutations within the internal protein structure. The structures were visualized using Chimera 1.14. software. Orange dots represent conservative changes, and red dots represent non-conservative changes at positions 62 and 123. The green region corresponds to the stem. 2D. Three-dimensional E protein monomer surface hydrophobicity representation based on Eisenberg’s scale. The representation illustrates changes in hydrophobicity for amino acid 62. The visualization was performed using PyMol 4.6.0 software and the Color h script

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