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Table 1 HPV type-specific distribution by cervical cytology

From: Enhanced disease progression due to persistent HPV-16/58 infections in Korean women: a systematic review and the Korea HPV cohort study

HPV type

Cervical cytology

Overalla

Normal

ASCUS+b

LSIL

HSIL

HSIL+c

Study

Sample size

Positive

Prevalence (95% CI)

Study

Sample size

Positive

Prevalence (95% CI)

Study

Sample size

Positive

Prevalence (95% CI)

Study

Sample size

Positive

Prevalence (95% CI)

Study

Sample size

Positive

Prevalence (95% CI)

Study

Sample size

Positive

Prevalence (95% CI)

High-risk

HPV-16

23

16,700

3,247

19.4 (18.8–20.0)

17

8,627

1,188

13.8 (13.0–14.5)

18

4,185

635

15.2 (14.1–16.3)

17

1,293

218

16.9 (14.8–18.9)

14

1,061

375

35.3 (32.5–38.2)

13

1,534

831

54.2 (51.7–56.7)

HPV-18

22

16,188

1,126

7.0 (6.6–7.3)

16

8,364

571

6.8 (6.3–7.4)

17

4,026

238

5.9 (5.2–6.6)

16

1,238

83

6.7 (5.3–8.1)

13

1,022

73

7.1 (5.6–8.7)

13

1,534

161

10.5 (9.0–12.0)

HPV-26

5

9808

26

0.3 (0.2–0.4)

4

6,193

16

0.3 (0.1–0.4)

4

2,753

7

0.3 (0.1–0.4)

5

587

3

0.5 (0.0–1.1)

3

181

0

0.0 (0.0–0.0)

0

0

0

NA

HPV-31

18

15,033

483

3.2 (2.9–3.5)

12

7,912

227

2.9 (2.5–3.2)

13

3,772

142

3.8 (3.2–4.4)

12

1,003

21

2.1 (1.2–3.0)

9

868

32

3.7 (2.4–4.9)

11

1,478

61

4.1 (3.1–5.1)

HPV-33

19

15,138

555

3.7 (3.4–4.0)

13

7,936

222

2.8 (2.4–3.2)

14

3,795

142

3.7 (3.1–4.3)

13

1,040

38

3.7 (2.5–4.8)

10

889

67

7.5 (5.8–9.3)

11

1,478

86

5.8 (4.6–7.0)

HPV-35

20

15,687

585

3.7 (3.4–4.0)

14

8,204

308

3.8 (3.3–4.2)

15

3,886

152

3.9 (3.3–4.5)

14

1,106

35

3.2 (2.1–4.2)

11

968

52

5.4 (4.0–6.8)

12

1,523

38

2.5 (1.7–3.3)

HPV-39

19

14,455

647

4.5 (4.1–4.8)

13

7,523

442

5.9 (5.3–6.4)

14

3,661

134

3.7 (3.1–4.3)

13

997

46

4.6 (3.3–5.9)

10

837

11

1.3 (0.5–2.1)

11

1,437

14

1.0 (0.5–1.5)

HPV-45

15

13,906

263

1.9 (1.7–2.1)

11

7,579

152

2.0 (1.7–2.3)

11

3,248

52

1.6 (1.2–2.0)

11

854

14

1.6 (0.8–2.5)

8

835

11

1.3 (0.5–2.1)

10

1,390

34

2.4 (1.6–3.3)

HPV-51

18

15,062

788

5.2 (4.9–5.6)

13

7,792

441

5.7 (5.1–6.2)

14

3,856

204

5.3 (4.6–6.0)

14

1,140

104

9.1 (7.5–10.8)

11

901

34

3.8 (2.5–5.0)

10

1,349

5

0.4 (0.0–0.7)

HPV-52

23

16,700

1,593

9.5 (9.1–10.0)

17

8,627

842

9.8 (9.1–10.4)

18

4,185

493

11.8 (10.8–12.8)

17

1,293

113

8.7 (7.2–10.3)

14

1,061

95

9.0 (7.2–10.7)

13

1,534

50

3.3 (2.4–4.1)

HPV-53

14

13,781

1,474

10.7 (10.2–11.2)

10

7,312

956

13.1 (12.3–13.8)

12

3,633

362

10.0 (9.0–10.9)

11

964

115

11.9 (9.9–14.0)

8

699

26

3.7 (2.3–5.1)

8

1,173

15

1.3 (0.6–1.9)

HPV-56

21

15,323

845

5.5 (5.2–5.9)

15

7,870

465

5.9 (5.4–6.4)

16

3,870

215

5.6 (4.8–6.3)

15

1,154

119

10.3 (8.6–12.1)

12

947

23

2.4 (1.4–3.4)

12

1,482

23

1.6 (0.9–2.2)

HPV-58

23

16,700

1,790

10.7 (10.2–11.2)

17

8,627

875

10.1 (9.5–10.8)

18

4,185

477

11.4 (10.4–12.4)

17

1,293

142

11.0 (9.3–12.7)

14

1,061

180

17.0 (14.7–19.2)

13

1,534

116

7.6 (6.2–8.9)

HPV-59

16

13,602

266

2.0 (1.7–2.2)

11

6,873

159

2.3 (2.0–2.7)

13

3,635

75

2.1 (1.6–2.5)

12

956

13

1.4 (0.6–2.1)

9

814

5

0.6 (0.1–1.2)

8

1,324

14

1.1 (0.5–1.6)

HPV-66

16

13,394

575

4.3 (3.9–4.6)

10

6,795

330

4.9 (4.3–5.4)

13

3,635

152

4.2 (3.5–4.8)

11

881

62

7.0 (5.3–8.7)

8

750

14

1.9 (0.9–2.8)

8

1,333

17

1.3 (0.7–1.9)

HPV-68

16

13,615

900

6.6 (6.2–7.0)

11

6,873

623

9.1 (8.4–9.7)

11

3,537

209

5.9 (5.1–6.7)

12

956

46

4.8 (3.5–6.2)

9

814

11

1.4 (0.6–2.1)

9

1,412

11

0.8 (0.3–1.2)

HPV-73

3

9,340

55

0.6 (0.4–0.7)

2

5,836

37

0.6 (0.4–0.8)

2

2,281

15

0.7 (0.3–1.0)

2

390

3

0.8 (0.0–1.6)

1

127

0

0.0 (0.0–0.0)

1

706

0

0.0 (0.0–0.0)

HPV-82

4

9,887

159

1.6 (1.4–1.9)

4

6,178

104

1.7 (1.4–2.0)

4

2,860

44

1.5 (1.1–2.0)

4

601

7

1.2 (0.3–2.0)

3

233

4

1.7 (0.0–3.4)

1

15

0

0.0 (0.0–0.0)

Low-risk

HPV-6

8

3,319

65

2.0 (1.5–2.4)

6

926

34

3.7 (2.5–4.9)

7

948

15

1.6 (0.8–2.4)

7

392

7

1.8 (0.5–3.1)

5

529

3

0.6 (0.0–1.2)

5

524

6

1.1 (0.2–2.1)

HPV-11

9

4,260

44

1.0 (0.7–1.3)

6

896

11

1.2 (0.5–1.9)

6

964

9

0.9 (0.3–1.5)

7

490

9

1.8 (0.6–3.0)

6

608

10

1.6 (0.6–2.7)

6

1,302

5

0.4 (0.0–0.7)

HPV-40

9

3,543

34

1.0 (0.6–1.3)

7

840

14

1.7 (0.8–2.5)

6

1,010

6

0.6 (0.1–1.1)

7

317

0

0.0 (0.0–0.0)

6

620

8

1.3 (0.4–2.2)

6

603

6

1.0 (0.2–1.8)

HPV-42

6

2,796

19

0.7 (0.4–1.0)

6

886

6

0.7 (0.1–1.2)

6

757

6

0.8 (0.2–1.4)

6

402

5

1.2 (0.2–2.3)

4

295

2

0.7 (0.0–1.6)

5

456

0

0.0 (0.0–0.0)

HPV-43

8

3,153

27

0.9 (0.5–1.2)

8

1,013

11

1.1 (0.4–1.7)

7

760

12

1.6 (0.7–2.5)

8

480

2

0.4 (0.2–1.0)

6

365

2

0.5 (0.0–1.3)

6

535

0

0.0 (0.0–0.0)

HPV-44

8

3,152

14

0.4 (0.2–0.7)

6

631

3

0.5 (0.1–1.0)

6

626

3

0.5 (0.0–1.0)

6

328

1

0.3 (0.0–0.9)

4

326

3

0.9 (0.0–2.0)

7

1,241

4

0.3 (0.0–0.6)

HPV-54

7

2,928

75

2.6 (2.0–3.1)

4

704

33

4.7 (3.1–6.2)

6

1,079

31

2.9 (1.9–3.9)

5

349

1

0.3 (0.0–0.8)

3

407

2

0.5 (0.0–1.2)

4

389

8

2.1 (0.6–3.5)

HPV-61

2

1,069

29

2.7 (1.7–3.7)

2

357

13

3.6 (1.7–5.6)

2

472

12

2.5 (1.1–4.0)

2

186

4

2.2 (0.1–4.2)

2

54

0

0.0 (0.0–0.0)

0

0

0

NA

HPV-70

10

9,827

768

7.8 (7.3–8.3)

7

4,200

447

10.6 (9.7–11.6)

8

3,221

258

8.0 (7.1–8.9)

8

672

43

6.4 (4.5–8.2)

6

601

15

2.5 (1.2–3.7)

6

1,110

5

0.5 (0.1–0.8)

HPV-72

3

755

8

1.1 (0.3–1.8)

3

206

5

2.4 (0.3–4.5)

3

217

2

0.9 (0.0–2.2)

3

162

1

0.6 (0.0–1.8)

3

140

0

0.0 (0.0–0.0)

1

15

0

0.0 (0.0–0.0)

HPV-81

4

1,719

24

1.4 (0.8–2.0)

4

598

11

1.8 (0.8–2.9)

4

647

9

1.4 (0.5–2.3)

4

285

4

1.4 (0.0–2.8)

3

152

0

0.0 (0.0–0.0)

3

37

0

0.0 (0.0–0.0)

Other

14

12,864

216

1.7 (1.5–1.9)

10

6,790

81

1.2 (0.9–1.5)

10

3,239

74

2.3 (1.8–2.8)

11

907

34

3.7 (2.5–5.0)

8

513

3

0.6 (0.0–1.2)

8

1,329

24

1.8 (1.1–2.5)

  1. ASCUS: Atypical squamous cells of uncertain significance; AGUS: Atypical glandular cells of undetermined significance; ASC-H: Atypical squamous cells without excluding HSIL; LSIL: Low-grade squamous intraepithelial lesion; HSIL: High-grade squamous intraepithelial lesion; CIS: Carcinoma in situ; ICC: Invasive cervical cancer; SCC: Squamous cell carcinoma; AC: Adenocarcinoma; AIS: Adenocarcinoma in situ; 95% CI: 95% Confidence interval
  2. aOverall prevalence by cytology was calculated using the sum of all types obtained from the Pap results
  3. bASCUS including AGUS and ASC-H
  4. cHSIL including CIS, ICC, SCC, AC, AIS, and cervical cancer
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