Fig. 6
From: Combination gene therapy for HIV using a conditional suicidal gene with CCR5 knockout
H7 cell line shows Tat dependent TK gene expression and cytotoxicity in the presence of GCV. a TZM, TK-SR39 or H7 cells were transduced with control or Tat expressing lentivirus particles. Cells were lysed 48Â h post infection and TK gene expression determined by western blotting. b TZM, TK-SR39 or H7 cells were transduced as in part A above and treated with the indicated concentrations of GCV. Percent viability was determined 48Â h post transduction using the Cell Titer Glo luciferase based assay