Table 1 Five miRNAs were selected for further research
From: Identification of cellular microRNA miR-188-3p with broad-spectrum anti-influenza A virus activity
Cellular miRNAs | Target | Targeting rate | Targeting rate of subtype | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
H1N1 | H1N2 | H2N2 | H3N2 | H5N1 | H5N6 | H7N3 | H7N4 | H7N7 | H7N9 | H9N2 | H10N8 | |||
miR-345-5p | PB2 | 26,805/28124 95.31% | 11,731/11821 99.24% | 26/27 96.30% | 80/81 98.77% | 14,907/15773 94.51% | 46/66 69.70% | 1/4 25% | 2/2 100% | 1/1 100% | 11/11 100% | 0/325 0% | 0/9 0% | 0/4 0% |
miR-188-3p | PB2 | 28,114/28124 99.96% | 11,814/11821 99.94% | 27/27 100% | 81/81 100% | 15,770/15773 99.98% | 66/66 100% | 4/4 100% | 2/2 100% | 1/1 100% | 11/11 100% | 325/325 100% | 9/9 100% | 4/4 100% |
miR-3183 | PB1 | 26,126/28124 92.90% | 10,577/11821 89.48% | 26/27 96.30% | 81/81 100% | 15,441/15773 97.9% | 0/66 0% | 0/4 0% | 0/2 0% | 1/1 100% | 0/11 0% | 0/325 0% | 0/9 0% | 0/4 0% |
miR-15a-3p | PA | 26,599/28124 94.58% | 10,455/11821 88.44% | 26/27 96.30% | 79/81 97.53% | 15,646/15773 99.19% | 41/66 62.12% | 2/4 50% | 2/2 100% | 1/1 100% | 11/11 100% | 323/325 99.38% | 9/9 100% | 4/4 100% |
miR-769-3p | NP | 27,347/28124 97.24% | 11,716/11821 99.11% | 27/27 100% | 80/81 98.77% | 15,516/15773 98.37% | 3/66 4.55% | 0/4 0% | 1/2 50% | 0/1 0% | 0/11 0% | 0/325 0% | 4/9 44.44% | 0/4 0% |