Evaluation on the use of Nanopore sequencing for direct characterization of coronaviruses from respiratory specimens, and a study on emerging missense mutations in partial RdRP gene of SARS-CoV-2

Table 4 Number of GISAID sequences by time, geographical regions and SNV status

Time	SNV	Africa	America	Asia/Middle East	Europe	Oceania	Subtotal	Total
Dec 2019	Absent	0	0	17	0	0	17	17
Dec 2019	Present	0	0	0	0	0	0	17
Jan 2020	Absent	0	18	318	24	9	369	384
Jan 2020	Present	0	0	15	0	0	15 (3.91%)	384
Feb 2020	Absent	1	108	418	122	17	666	688
Feb 2020	Present	0	2	18	1	1	22 (3.20%)	688
Mar 2020	Absent	72	319	660	10,816	1006	12,873	13,435
Mar 2020	Present	22	63	21	407	49	562 (4.18%)	13,435
Apr 2020	Absent	27	1,803	455	4233	219	6,737	7082
Apr 2020	Present	30	90	25	194	6	345 (4.87%)	7082
May 2020	Absent	0	118	87	330	15	550	567
May 2020	Present	1	2	6	6	2	17 (3.00%)	567
Subtotal	Absent	100	2366	1955	15,525	1266	21,212	22,173
Subtotal	Present	53	157	85	608	58	961	22,173
Total		153	2523	2,040	16,133	1324	Global
% with SNV		34.64	6.22	4.17	3.77	4.38	4.33

ISSN: 1743-422X