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Fig. 4 | Virology Journal

Fig. 4

From: The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon

Fig. 4

Y73F and S83A substitution affects IFN-β antagonistic properties of NS1. a, b 293 T cells were infected with rSIV or mutated virus at an MOI of 1 for different times. IFN-β and ISG56 mRNA levels in the cell lysates were quantified by real-time PCR. Values represent n-fold expression of MOCK-infected cells and are displayed as the means ± SDs of three independently repeated experiments. “MOCK” represents samples from uninfected control cells

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