Fig. 1From: Highly pathogenic avian influenza H7N9 viruses with reduced susceptibility to neuraminidase inhibitors showed comparable replication capacity to their sensitive counterpartsReplication kinetics of recombinant viruses in MDCK cells. Cells were inoculated with the recombinant viruses at 37 °C, and culture supernatants were harvested at 0, 18, 24, 48, 72 and 96 h post-inoculation. Virus titers were determined on MDCK cells. Growth curve of the rg006-NA292R(119E, 246A, 274H) in MDCK cells was in red, round; rg006-NA119V viruses were in blue, square (a); rg006-NA246T virus in purple, square (b); rg006-NA274Y virus in brown square (c); rg006-NA292Kviruses in green, square (d). Each data point represents the log10 mean ± SD TCID50/mL from at least two independent tests. *P < 0.05Back to article page