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Table 7 Optimal predicted HLA-I-restricted epitopes selected from HPV-33 E6 and E7

From: Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

Target Protein

Start

Length

Peptide

Percentile Rank

Binding Core in HLA-II predicted epitopes

HPV-33 E6

41

14

EVYDFAFADLTVVY

0.1

YDFAFADLT/DFAFADLTV/FAFADLTVV

42

14

VYDFAFADLTVVYR

0.1

YDFAFADLT/DFAFADLTV/FAFADLTVV

43

14

YDFAFADLTVVYRE

0.1

YDFAFADLT/DFAFADLTV/FAFADLTVV

44

14

DFAFADLTVVYREG

0.1

DFAFADLTV/FAFADLTVV

45

14

FAFADLTVVYREGN

0.1

FAFADLTVV

HPV-33 E7

52

10

YYIVTCCHTC

0.6

YYIVTCCHT

59

8

HTCNTTVR

0.6

 

77

8

RTIQQLLM

0.1

 

77

14

RTIQQLLMGTVNIV

0.5

 

81

10

QLLMGTVNIV

0.55

 

82

9

LLMGTVNIV

0.4

 
  1. Note: The column of “Binding Core in HLA-II predicted epitopes” refers to the binding core of predicted HLA-II epitopes present in optimal HLA-I epitopes