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Fig. 3 | Virology Journal

Fig. 3

From: The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

Fig. 3

HBV clearance still occurs in 20 μg e/core-null pAAV/HBV1.2 plasmid-injected mice. WT mice were hydrodynamically injected with 6 μg or 20 μg pAAV/HBV1.2 plasmid. Liver HBcAg expression (a) was detected at day 3 AHI. (original magnification: 40×) (b) serum levels of anti-HBc was measured at indicated mice. c, d C57BL/6 mice were hydrodynamically injected with various plasmids as shown. Serum levels of HBsAg were measured at indicated time points. d Positive rate of serum HBsAg after HBV plasmid injection

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