Fig. 5From: High serum levels of pregenomic RNA reflect frequently failing reverse transcription in hepatitis B virus particlesLevels of precore RNA and pgRNA in liver tissue (a) and serum (b) as measured by digital PCR. The level of pgRNA was on average 30 times higher (1.5 log10 units) than precore RNA in liver tissue, as compared with 200 times higher (2.3 log10 units) in serum, indicating that precore RNA is encapsidated and secreted to serum 6.6 times less effectively than pgRNABack to article page