Fig. 2From: The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathwayThe gross pathological and histopathological changes of xenografts in nude mouse. a Nude mice injected with HBV replication L02 cell lines stably expressing wild type, substitute and truncated HBsAg, respectively; (b) nude mice injected with L02 cell lines stably expressing wild type, substitute and truncated HBsAg, respectively. The tumor volume was significantly higher in nude mice with pHBV4.1-HBs(sW172*) or pcDNA3.1-HBs(sW172*) as compared to other groupsBack to article page