Position i | Amino acid α | Position j | Amino acid β | eij (α, β) | Time trend | Minor INSTI resistance mutation | INSTI-selected mutation |
---|---|---|---|---|---|---|---|
10 | D | 122 | I | 0.0683 | * | ||
10 | E | 122 | I | −0.0753 | * | ||
11 | D | 119 | S | −0.0940 | * | ||
11 | D | 154 | I | −0.0527 | * | * | |
11 | D | 154 | M | 0.0335 | * | ||
11 | E | 119 | S | 0.0909 | * | ||
11 | E | 154 | I | 0.0577 | * | * | |
11 | E | 154 | M | −0.0368 | * | ||
17 | N | 124 | A | 0.0690 | * | ||
17 | S | 124 | A | −0.0598 | * | ||
23 | A | 201 | I | −0.0490 | * | ||
23 | A | 201 | V | 0.0525 | * | ||
23 | V | 201 | I | 0.0432 | * | ||
23 | V | 201 | V | −0.0443 | * | ||
31 | I | 154 | I | −0.0438 | * | ||
31 | V | 154 | I | 0.0352 | * | ||
39 | C | 154 | I | −0.0329 | * | ||
39 | C | 201 | I | 0.0776 | * | ||
39 | C | 201 | V | −0.0725 | * | ||
39 | S | 154 | I | 0.0384 | * | ||
39 | S | 201 | I | −0.0859 | * | ||
39 | S | 201 | V | 0.0828 | * | ||
72 | I | 265 | A | 0.0587 | * | ||
72 | I | 265 | V | −0.0612 | * | ||
72 | V | 265 | A | −0.0622 | * | ||
72 | V | 265 | V | 0.0676 | * | ||
101 | I | 111 | K | −0.0743 | * | ||
101 | I | 111 | T | 0.0334 | * | ||
101 | I | 154 | I | −0.0462 | * | * | |
101 | I | 154 | M | 0.0645 | * | * | |
101 | L | 154 | I | 0.0606 | * | * | |
101 | L | 154 | M | −0.0695 | * | ||
112 | A | 124 | A | 0.0205 | * | ||
112 | I | 124 | A | 0.0205 | * | ||
112 | I | 201 | I | 0.0482 | * | ||
112 | I | 201 | V | −0.0538 | * | ||
112 | T | 124 | A | −0.0447 | * | ||
112 | T | 201 | I | −0.0483 | * | ||
112 | T | 201 | V | 0.0490 | * | ||
119 | G | 122 | I | 0.0576 | * | ||
119 | P | 122 | I | 0.1303 | * | ||
119 | S | 122 | I | −0.1695 | * | * | |
119 | T | 122 | I | −0.0194 | * | ||
124 | A | 125 | T | 0.0266 | * | ||
124 | A | 125 | V | −0.0288 | * | ||
124 | A | 211 | K | −0.0568 | * | ||
124 | A | 211 | R | 0.0263 | * | ||
124 | A | 211 | T | 0.0294 | * | ||
124 | S | 125 | A | 0.0244 | * | ||
124 | T | 125 | A | −0.0205 | * | ||
154 | I | 165 | I | 0.0893 | * | * | |
154 | I | 165 | V | −0.0976 | * | * | |
154 | I | 256 | D | 0.0333 | * | ||
154 | I | 256 | E | −0.0369 | * | * | |
154 | I | 265 | A | 0.0520 | * | * | |
154 | I | 265 | V | −0.0484 | * | * | |
154 | M | 165 | I | −0.1011 | * | ||
154 | M | 165 | V | 0.1118 | * | ||
154 | M | 256 | E | 0.0525 | * | ||
154 | M | 265 | A | −0.0496 | * | ||
154 | M | 265 | V | 0.0482 | * | ||
157 | Q | 160 | K | −0.0632 | * | ||
157 | Q | 160 | Q | 0.0649 | * | ||
201 | I | 256 | D | 0.0623 | * | ||
201 | I | 256 | E | −0.0611 | * | * | |
201 | I | 265 | A | 0.0484 | * | * | |
201 | I | 265 | V | −0.0466 | * | * | |
201 | V | 256 | E | 0.0604 | * | ||
201 | V | 265 | A | −0.0535 | * | ||
201 | V | 265 | V | 0.0547 | * |