Table 1 Quantification of Ad5 transduction and CAR expression across the panel of cell lines
From: Integrin αvβ5 is a primary receptor for adenovirus in CAR-negative cells
Transduction | CAR Expression | |||
|---|---|---|---|---|
Cell Line | % positive | MFI | % positive | MFI |
SkMel2 | 97.1 | 575 | 98.3 | 68.3 |
MDA-MB-231 | 69.3 | 438 | 93.5 | 31.2 |
BT549 | 35.5 | 86.2 | 42.2 | 12.6 |
MDA-MB-453 | 58.1 | 78.3 | 98.1 | 40 |
MDA-MB-435 | 79.2 | 657 | 0.5 | 3.9 |
MCF7 | 67 | 673 | 2.9 | 4.9 |
WM278 | 45.9 | 186 | 2.8 | 12.6 |
T47D | 13.6 | 50.6 | 71.8 | 32.2 |