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Figure 1 | Virology Journal

Figure 1

From: Characterisation of a GII-4 norovirus variant-specific surface-exposed site involved in antibody binding

Figure 1

GII-4 Norovirus Major Sturctural Protein. (a) Schematic representing the norovirus VP1 protein, highlighting the hypervariable P2 domain and putative epitopes Site A and Site B (as described in Allen et al., 2008). (b) Table showing amino acid variation at Site A and Site B in the period 1999-2006, as previously described in (Allen et al., 2008). Strains used in the work described here are highlighted. (c) Model of the norovirus VP1 P domain showing the location of Site A and Site B in the three-dimensional protein (structure from Cao et al., 2007). (d) Electron micrograph showing GII-4v2 VLPs purified from Sf 9 cells, the morphology of which is representative for all VLPs described here. Magnification is 105 000× and VLPs are stained with 1.5% phosphotungstic acid. Scale bar is 100 nm.

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Virology Journal

ISSN: 1743-422X