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Table 1 Virus titers in the tissues of infected mice

From: Transmission of H7N9 influenza virus in mice by different infective routes

Virusa

Days post-infection

Virus titer (log10TCID50 ± SD)

  

Heart

Liver

Spleen

Lung

Kidney

Intestine

Brain

Nose

A/CA/07/09 (H1N1)

5

NPd

-b

+

4.83 ± 1.7

-

-

-

NP

A/SZ/406H/06 (H5N1)

5

NP

3.62 ± 1.1

1.62 ± 0.23

3.50 ± 1.92

1.17 ± 0.32

1.38 ± 0.27

2.17 ± 0.41

NP

A/Anhui/1/2013 (H7N9)

1

-

-

-

4.00 ± 1.20

-

-

-

3.50 ± 1.38

2

-

0.81

1.50

5.50 ± 1.90

2.00

-

+c

2.50 ± 0.75

3

-

0.75

-

5.00 ± 1.85

-

 

-

2.50 ± 0.75

5

-

-

-

6.00 ± 2.15

-

0.86 ± 0.13

-

3.50 ± 1.38

 

7

-

-

-

3.50 ± 1.77

-

0.75

-

2.00 ± 0.38

  1. aMice were infected with influenza viruses at a dose of 106 TCID50.
  2. bViable virus was not detected after three passages in MDCK cells.
  3. cCyotpathic effects were observed but TCID50 values were less than 0.5.
  4. dNP, Not performed.
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Virology Journal

ISSN: 1743-422X