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Table 1 HCV infection status in relation to four S/Co ranges in four assays

From: A study based on four immunoassays: Hepatitis C virus antibody against different antigens may have unequal contributions to detection

Assays

Groups

S/Co ranges

<ā€‰1

1ā€“2.5

2.5ā€“4

>ā€‰4

Ortho ELISA

Viremia (n)

0

1

0

263

%

0.0

0.4

0.0

99.6

Consistent (n)

0

47

34

142

%

0.0

21.1

15.2

63.7

Discrepant (n)

80

73

26

16

%

41.0

37.4

13.3

8.2

Murex ELISA

Viremia (n)

0

22

29

213

%

0.0

8.3

11.0

80.7

Consistent (n)

0

29

21

173

%

0.0

13.0

9.4

77.6

Discrepant (n)

86

41

17

51

%

44.1

21.0

8.7

26.2

Architect CMIA

Viremia (n)

0

0

2

262

%

0.0

0.0

0.8

99.2

Consistent (n)

0

70

20

133

%

0.0

31.4

9.0

59.6

Discrepant (n)

29

92

47

27

%

14.9

47.2

24.1

13.8

Elecsys ECLIA

Viremia (n)

0

0

0

264

%

0.0

0.0

0.0

100.0

Consistent (n)

0

0

0

223

%

0.0

0.0

0.0

100.0

Discrepant (n)

152

2

3

38

%

77.9

1.0

1.5

19.5

  1. aIn each of the four assays, specimens were classified into three groups: (1) HCV RNA positive group (Viremia, nā€‰=ā€‰264); (2) HCV RNA negative, anti-HCV consistent group (Consistent, nā€‰=ā€‰223); (3) HCV RNA negative, anti-HCV discrepant group (Discrepant, nā€‰=ā€‰195). In each group, the specimens were further divided into four S/Co ranges with specific numbers and percentages. S/Co valueā€‰<ā€‰1.0 was considered as anti-HCV negative while S/Co valueā€‰>ā€‰4 was considered strongly anti-HCV positive