Table 3 The viral load, levels of inflammatory markers and lymphocyte subsets of the study subjects according to disease severity of COVID-19 on admission to hospital
Laboratory findings | Disease severity of COVID-19 | Statistic parameter | |||
|---|---|---|---|---|---|
(mean ± SD) | AS (n = 11) | MS (n = 26) | SCS (n = 11) | F value | P value |
Ct values | 31.9 ± 2.6 | 31.0 ± 3.0 | 31.6 ± 2.8 | 0.398 | 0.674 |
B cells (%) | 28.9 ± 14.8 | 13.3 ± 7.7 | 9.6 ± 6.6 | 7.018 | 0.002** |
NK cells (%) | 6.6 ± 5.1 | 3.8 ± 1.8 | 3.5 ± 1.1 | 1.286 | 0.286 |
CD 3 + T cells (%) | 61.7 ± 7.8 | 63.9 ± 12.1 | 52.1 ± 13.2 | 4.079 | 0.024* |
CD3 + CD4 + T cells (%) | 33.3 ± 5.6 | 36.1 ± 9.7 | 30.3 ± 8.7 | 1.764 | 0.183 |
CD3 + CD8 + T cells (%) | 23.1 ± 6.3 | 24.2 ± 10.5 | 17.0 ± 5.6 | 2.634 | 0.083 |
CD4 + /CD8 + ratio (%) | 1.6 ± 0.8 | 1.8 ± 0.9 | 1.9 ± 0.8 | 1.764 | 0.183 |
IL2 (pg/mL) | 4.8 ± 6.2 | 4.8 ± 4.1 | 8.3 ± 6.7 | 1.834 | 0.172 |
IL4 (pg/mL) | 3.8 ± 2.6 | 3.8 ± 1.8 | 3.4 ± 1.1 | 0.161 | 0.852 |
IL5 (pg/mL) | 5.9 ± 6.4 | 5.3 ± 4.4 | 6.3 ± 4.9 | 0.179 | 0.836 |
IL6 (pg/mL) | 7.0 ± 10.2 | 6.0 ± 11.3 | 572.7 ± 1326.4 | 3.479 | 0.039* |
IL8 (pg/mL) | 52.9 ± 123.0 | 88.8 ± 90.8 | 885.7 ± 1920.0 | 3.348 | 0.044* |
IL10 (pg/mL) | 2.9 ± 1.1 | 2.7 ± 0.8 | 7.0 ± 7.6 | 5.819 | 0006** |
TNF-α (pg/mL) | 19.3 ± 43.6 | 58.2 ± 60.8 | 9.5 ± 7.5 | 4.689 | 0.014* |
INF-α (pg/mL) | 4.0 ± 3.9 | 5.7 ± 9.3 | 3.4 ± 0.7 | 0.451 | 0.640 |
INF-γ (pg/mL) | 16.1 ± 34.8 | 26.9 ± 66.9 | 11.5 + 8.3 | 0.390 | 0.680 |