Fig. 1From: Advances in HBV infection and replication systems in vitroSchematic diagram of HBV entry into HepG2-NTCP cell mediated by NTCP. HBV interacts with the heparan sulfate proteoglycan on the cell surface and binds to the specific receptor NTCP which were overexpressed on the HepG2-NTCP cell, and then enters it. For detailed information, see the text. HSPG: heparan sulfate proteoglycan; NTCP: Na+-taurocholate co-transporting polypeptide; cccDNA: covalently closed circular DNA.Back to article page