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Table 1 Characteristics of 139 hospitalized patients due to severe acute respiratory infection by HRSV genotypes

From: Differences in viral load among human respiratory syncytial virus genotypes in hospitalized children with severe acute respiratory infections in the Philippines

HRSV genotype

NA1

ON1

BA9

P value

n = 17

n = 51

n = 71

 

Age in months, median [IQR]

10 [3–19]

6 [3–11]

11 [5–19]

0.026*

Males (%)

10 (58.8)

33 (64.7)

41 (57.7)

0.733**

Days between illness onset and specimen collection, median [IQR]

4 [3–5]

5 [4–7]

4 [3–7]

0.074*

Symptoms (%)

    

 Fever

13 (76.5)

39 (76.5)

61 (85.9)

0.361**

 Cough

17 (100.0)

51 (100.0)

71 (100.0)

-

 Chest indrawing

17 (100.0)

51 (100.0)

71 (100.0)

-

 Difficulty of breathing

12 (70.6)

41 (80.4)

50 (70.4)

0.436**

 Inability of drink

0 (0.0)

1 (2.0)

5 (7.0)

0.255**

 Neurological signs

0 (0.0)

5 (9.8)

5 (7.4)

0.398**

Peripheral oxygen saturation < 90 % (%)

1 (5.9)

6 (11.8)

11 (15.5)

0.542**

Viral coinfection (%)

0 (0.0)

7 (13.7)

4 (8.4)

0.114**

Viral load (Log10 RNA copies/μL), median [IQR]

 

 All ages

6.5 [5.8–6.8]

5.4 [4.6–6.2]

5.4 [4.8–6.1]

<0.001***

< 6 months

(n = 6)

(n = 27)

(n = 21)

 

6.6 [6.2–7.2]

5.7 [4.7–6.4]

5.8 [5.2–6.2]

0.032*

  1. HRSV: Human Respiratory Syncytial Virus, Neurological sign: history of convulsion or lethargic/asleep
  2. *Kruskal-Wallis test, **chi-square test, ***one-way ANOVA
  3. IQR: 25th and 75th Interquartile range, One patient positive for genotype GB2 was excluded from this analysis