Cases | Molecular detection | Serology detection | |||||
---|---|---|---|---|---|---|---|
 | Direct RT-PCR for pan-enterovirus | Virus isolation/serotyping | ELISA testing for Coxsackievirus IgM of 22 acute-phase sera | Neutralization Test | |||
 | CSF | Stool | CSF | Stool |  | Neutralization titer in acute-phase | Neutralization titer in convalescent |
1 | + | + | +/CVA9 | +/CVA9 | + | <1:20 | 1:501 |
2 | + | + | - | - | + | <1:20 | 1:1000 |
3 | + | + | - | +/CVA9 | + | <1:20 | >1:1024 |
4 | + | / | +/CVA9 | / | - | / | / |
5 | - | + | - | +/CVA9 | + | / | / |
6 | - | + | - | +/CVA9 | + | / | / |
7 | - | + | - | +/CVA9 | + | / | / |
8 | - | + | - | +/CVA9 | + | / | / |
9 | - | + | - | - | + | / | / |
10 | - | + | - | - | - | / | / |
11 | / | + | / | - | - | / | / |
12 | / | + | / | - | - | / | / |
13 | / | + | / | - | - | / | / |
14 | / | - | / | - | + | / | / |
15 | / | - | / | - | + | / | / |
Total | 4 | 12 | 2//CVA9 | 6//CVA9 | 10 | At least four times higher for all three pairs of paired serum samples |