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Table 1 Demographic, clinical and socioeconomic characteristics of the children with A/H1N1 influenza infection, by the presence or absence of the H275Y mutation.

From: Clinical importance and impact on the households of oseltamivir-resistant seasonal A/H1N1 influenza virus in healthy children in Italy

Characteristics Oseltamivir-resistant seasonal A/H1N1 influenza virus (n = 19) Wild-type seasonal A/H1N1 influenza virus (n = 124)
Demographic data   
   No. of males (%) 11 (57.9) 73 (58.9)
   Mean age ± SD, years 4.33 ± 3.61 3.39 ± 2.58
   Previous use of neuraminidase inhibitors, no. (%) 0 (0.0) 0 (0.0)
CT, mean ± SD 25.48 ± 4.44 26.94 ± 4.57
Clinical presentation   
   Common cold, No. (%) 4 (21.0) 28 (22.6)
   Pharyngitis, No. (%) 5 (26.3) 34 (27.4)
   Acute otitis media, No. (%) 3 (15.8) 18 (14.5)
   Acute bronchitis, No. (%) 4 (21.0) 26 (21.0)
   Pneumonia, No. (%) 1 (5.3) 8 (6.5)
   Gastroenteritis, No. (%) 1 (5.3) 6 (4.8)
   Fever without source, No. (%) 1 (5.3) 4 (3.2)
Clinical outcome   
   Hospitalisation, No. (%) 4 (21.0) 21 (16.9)
   Median number of lost school days (range) 6 (1-12) 5 (1-10)
Pharmacological treatment   
   Antibiotics, No. (%) 13 (68.4) 88 (70.9)
   Antivirals, No. (%) 0 (0.0) 0 (0.0)
   Antipyretics, No. (%) 16 (84.2) 99 (79.8)
Socioeconomic impact on households   
   Similar disease among family members, No. (%) 10 (52.6) 52 (41.9)
   Hospitalisations, No. (%) 1 (5.3) 0 (0.0)
   Median number of lost parental working days (range) 3 (1-11) 3 (1-9)
   Median number of lost sibling working days, (range) 4 (2-14) 3 (2-15)
  1. CT, cycle thresold; SD, standard deviation. No significant between-group differences.