Figure 8From: Genome-wide diversity and selective pressure in the human rhinovirusLocation of diversifying residues and functional residues in the 3D polymerase. Front view (A), side view of fingers subdomain (B), back view (C), and side view of thumb subdomain (D) of the HRV14 3D polymerase structure (Love et al., 2004). Cyan, palm subdomain residues; blue, catalytic residues; green, residues implicated in VPg and CRE binding; pink, potential oligomerization interface I residues. Diversifying residues are shown in red, shaded according to their corresponding dN/dS values indicated by scale bar below panel C; yellow, diversifying residues that directly overlap functional residues. Insets A-D, provided for orientation to 3D polymerase subdomains: red, fingers subdomain; cyan, palm subdomain; purple, thumb subdomain; yellow, N-terminal residues.Back to article page