Figure 7From: Genome-wide diversity and selective pressure in the human rhinovirusLocation of diversifying residues and functional residues in the 3C protease. Three different views of diversifying residues in the HRV2 3C protease relative to protease active site residues (blue; (Matthews et al., 1999)) and residues implicated in RNA binding and VPg binding (green; (Matthews et al., 1999). A. Relative to both protease and RNA binding/VPg interacting domain. B. Relative to RNA binding/VPg interaction domain. C. Relative to the proteolytic active site (Matthews et al., 1999). Diversifying residues are shown in red, shaded according to their corresponding dN/dS values indicated by the scale bar; yellow, diversifying residues that directly overlap functional residues.Back to article page